All Things Chromatography

NIH Research Festival

This week, we're participating in the 29th Annual Research Festival at the National Institutes of Health.

The festival features workshops and posters on a wide variety of subjects, from RNA Biology and Theapeutics to chemical biology and research on vaccines.

We will be at Booth #267 at the exhibition on September 17 and 18.

If you will be at the NIH Research Festival, we hope you will stop by booth 267. 

 

NIH-booth-267

Topics: NIH

Thin Layer Chromatography used in DNA aging research

Excerpts from a paper posted on the U.S. National Library of Medicine and the National Institutes of Health web site DNA strandstitled:

TLC-based detection of methylated cytosine: application to aging epigenetics

5-Methylcytosine (m(5)C) has a plethora of functions and roles in various biological processes including human diseases and aging. A TLC-based fast and simple method for quantitative determination of total genomic levels of m(5)C in DNA is described, which can be applicable to aging research with respect to rapid and high throughput screening and comparison. Using this method, an example of the analysis of global alternations of m(5)C in serially passaged human skin fibroblasts is provided, which shows age-related global hypomethylation during cellular aging in vitro.

Click Here to access the paper.

Topics: National Institutes of Health, chromatography, Thin Layer Chromatography, testing, test, DNA, aging, NIH